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环境内分泌干扰物(environmental endocrine disruptors,EEDs)是一类存在于环境中能改变机体内分泌功能并对机体、子代或亚群引起有害效应的化学物质。包括拟雌激素类、拟睾酮类、拟甲状腺素类、拟其他内分泌功能类。这些化合物广泛存在于日常生活和工作的环境中,可通过多种途径和方式主动或被动进入动物和人体内,而有些EEDs还可通过脐带血进入胎儿体内。大量实验及流行病学资料表明EEDs可引起子代早产、低出生体质量、肥胖、代谢紊乱、泌尿生殖系统异常等方面异常。
Environmental endocrine disruptors (EEDs) are a group of chemicals that exist in the environment that alter the endocrine function of the body and cause deleterious effects on the body, offspring, or subpopulations. Including pseudo-estrogens, pseudo-testosterone, thyroxins, to be other types of endocrine function. These compounds are widely present in everyday and working settings and can be actively or passively introduced into animals and humans in a variety of ways and means. Some EEDs can also enter the fetus through cord blood. A large number of experimental and epidemiological data show that EEDs can cause abnormalities in progeny premature birth, low birth weight, obesity, metabolic disorders, genitourinary system abnormalities.