论文部分内容阅读
测定了５６例ＮＩＤＤＭ患者血浆皮内素水平和红细胞膜微粘度。结果显示：ＮＩＤＤＭ患者血浆内皮素及红细胞膜微粘度明显较正常人增高，并且ＮＩＤＤＭ思考血浆内皮素（ＥＴ）与空腹血糖及红细胞膜微粘度呈明显正相关。与血浆胰岛素呈明显负相关。说明长期高血糖可导致ＮＩＤＤＭ患者红细胞膜微粘度增高，而引起微循环障碍，也可导致内皮细胞损伤，使ＥＴ释放增加，而内皮素引起的缩血管作用又加重微循环障碍，上述恶性循环可能与糖尿病微血管病变发生有关。
Determination of 56 cases of NIDDM plasma endothelin levels and erythrocyte membrane microviscosity. The results showed that: the plasma endothelin and erythrocyte membrane microviscosity of NIDDM patients was significantly higher than that of normal people, and NIDDM thought plasma ET (ET) was positively correlated with fasting blood glucose and erythrocyte membrane microviscosity. There was a clear negative correlation with plasma insulin. Long-term hyperglycemia can cause long-term high blood viscosity of erythrocyte membrane in patients with NIDDM caused by microcirculation, but also can lead to endothelial cell damage, ET release increased, and endothelin-induced vasoconstriction aggravate microcirculation, the vicious cycle may be Diabetic microangiopathy and the occurrence.