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晚期糖基化终产物 (AGE)是蛋白质的氨基与糖的醛基发生非酶性糖基化反应的终产物 ,在慢性肾功能衰竭和糖尿病肾病并发症的发生和发展中起重要作用。本文就AGE和AGE受体在肾脏病变中的作用作一综述
Advanced glycation end products (AGEs) are the end products of the non-enzymatic glycosylation of the amino group of a protein with the aldehyde group of a sugar, and play an important role in the development and progression of complications of chronic renal failure and diabetic nephropathy. This article reviews the role of AGE and AGE receptors in renal disease