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目的:研究大豆卵磷脂的抗疲劳及抗氧化作用。方法:小鼠经口给予大豆卵磷脂30天后,采用负重游泳实验,观察记录小鼠游泳死亡时间;检测血清尿素氮、肝糖原;测定血清和肝匀浆超氧化物歧化酶(SOD)活性、谷胱甘肽过氧化物酶(GSH-Px)活力、丙二醛(MDA)含量。结果:给予大豆卵磷脂后,与对照组相比,实验组小鼠负重游泳时间明显延长,肝糖原消耗量减少,降低运动后血清尿素氮水平(P<0.05);升高小鼠血清和肝匀浆SOD活性及GSH-Px活力,降低MDA的含量(P<0.05)。结论:大豆卵磷脂具有抗疲劳和抗氧化作用。
Objective: To study the anti-fatigue and antioxidant effects of soybean lecithin. Methods: The mice were orally administered with soybean lecithin for 30 days. The swimming time of mice was recorded by swimming under the load. The serum urea nitrogen and hepatic glycogen were measured. The activity of superoxide dismutase (SOD) in serum and liver homogenate , Glutathione peroxidase (GSH-Px) activity, malondialdehyde (MDA) content. Results: Compared with the control group, the swimming time of mice in the experimental group was significantly prolonged and the consumption of hepatic glycogen was decreased, the level of serum urea nitrogen was decreased after exercise (P <0.05); the serum and Liver homogenate SOD activity and GSH-Px activity, reduce the content of MDA (P <0.05). Conclusion: Soy lecithin has anti-fatigue and anti-oxidation effects.