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目的 本文应用速避凝 (即低分子肝素 )治疗急性脑梗塞病人 12 0例 ,疗效比较及副作用的观察。方法 对于12 0例急性脑梗塞病人 ,在 2 4～ 48小时内 ,脐周皮下注射速避凝 0 4ml,每日 2次 ,共 10天 ,其它治疗均同对照组 (配对 12 0例 ) ,10天后比较病人肌力提高级别判定疗效 ,同时监测治疗前后血常规 ,血小板 ,纤维蛋白原 ,PT(凝血酶原 )及肝、肾功能等变化 ,观察有无出血等副作用。结果 治疗组 :显效 6 8 3% ( 82 / 12 0 ) ,总有效率达 85 % ( 10 2 / 12 0 ) ;对照组 :显效 5 4 2 % ( 6 5 /12 0 ) ,总有效率 (显效 +有效 ) 6 6 7% ( 80 / 12 0 ) ,两组有非常显著性差异 ( P <0 0 1)。观察副作用无明显变化 ( P >0 0 5 ) ,未发现有皮肤粘膜及消化道出血现象。结论 速避凝治疗脑梗塞安全有效 ,且使用方便 ,值得临床医师推广使用
Objective To evaluate the efficacy and side effects of 120 cases of acute cerebral infarction treated with rapid contraception (low molecular weight heparin). Methods A total of 120 patients with acute cerebral infarction were treated with subcutaneous hypodermic injection of 0 4ml subcutaneously twice a day for 10 days in 24 to 48 hours. Other treatments were the same as those in the control group (matched 120 cases) Ten days later, the patient’s muscle strength was compared to determine the level of efficacy. At the same time, blood routine, platelet, fibrinogen, PT (prothrombin) and liver and kidney function were monitored before and after treatment, and the side effects such as bleeding were observed. Results In the treatment group, the effective rate was 68.3% (82/120) and the total effective rate was 85% (10 2/12 0). In the control group, the effective rate was 54.2% (65/12 0) and the total effective rate Effective and effective) 6 6 7% (80/12 0), there was a significant difference between the two groups (P 0 01). No significant changes in side effects observed (P> 0 05), found no skin and mucous membranes and gastrointestinal bleeding. Conclusion Avoidance of cerebral infarction in the treatment of cerebral infarction safe and effective, and easy to use, it is worth promoting the use of clinicians