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目的 观察腹腔转移性肿瘤应用热化疗腹腔灌注联合体外加热治疗的临床效果。方法应用DDP、MMC热化疗灌注同时联合体外超声或微波加热治疗腹腔转移性肿瘤 2 0例。结果 治疗后症状缓解率为 19/ 2 0 ,有效率为 18/ 2 0 ,1年生存率 10 / 18,毒副作用为胃肠反应 (7/ 2 0 ) ,白细胞降低(5 / 2 0 ) ,血小板降低 (9/ 2 0 ) ,治疗后兔疫功能有所提高 (P <0 .0 5 )。结论 热化疗腹腔灌注联合体外加热治疗腹腔转移肿瘤 ,副作用小 ,疗效好 ,能明显缓解患者症状 ,提高其免疫功能
Objective To observe the clinical effect of thermochemotherapy peritoneal perfusion combined with external heating in metastatic tumors of the abdominal cavity. Methods 20 cases of peritoneal metastatic tumors were treated with DDP and MMC thermochemotherapy combined with ultrasound or microwave heating in vitro. Results After treatment, the symptom relief rate was 19/20, the effective rate was 18/20, the 1-year survival rate was 10/18, the side effects were gastrointestinal reaction (7/20), leukopenia (5/20) The platelet count decreased (9/20), and the immunity of rabbits increased after treatment (P <0.05). Conclusion Intraperitoneal perfusion of thermochemotherapy and extracorporeal heating treatment of intraperitoneal tumor metastasis with small side effects and good curative effect can obviously relieve the symptoms of patients and improve their immune function