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目的:观察无创双水平正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床效果。方法:慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者30例,在常规抗感染、解痉平喘、止咳化痰治疗基础上,应用无创双水平正压通气辅助治疗,观察通气治疗24 h时pH、心率、呼吸、动脉血氧分压、动脉血二氧化碳分压、动脉血氧饱和度水平,并与通气治疗前比较。结果:好转28例(93.3%),通气治疗后动脉血氧分压、动脉血氧饱和度较治疗前上升(P<0.05),动脉血二氧化碳分压较治疗前下降(P<0.05)。2例无效改行有创通气。结论:无创双水平正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭疗效满意。
Objective: To observe the clinical effect of noninvasive bi-level positive pressure ventilation in treating patients with chronic obstructive pulmonary disease (COPD) and type Ⅱ respiratory failure. Methods: Thirty patients with chronic obstructive pulmonary disease and type Ⅱ respiratory failure were treated with noninvasive bi-level positive pressure ventilation on the basis of routine anti-infective, antispasmodic and anti-asthma, cough and phlegm treatment. The changes of pH, heart rate , Respiration, arterial partial pressure of oxygen, partial pressure of arterial carbon dioxide, arterial oxygen saturation, and compared with before ventilation. Results: In 28 cases (93.3%) improved, arterial partial pressure of oxygen and arterial oxygen saturation increased (P <0.05) and arterial partial pressure of carbon dioxide decreased (P <0.05). 2 cases ineffective diverting invasive ventilation. Conclusion: Noninvasive bi-level positive pressure ventilation is effective in treating chronic obstructive pulmonary disease with type Ⅱ respiratory failure.