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目的:分析经阴道及经腹超声结合血清指标检测对宫外孕诊断的临床准确率及临床意义,为临床推广提供依据。方法:选取2012年6月至2015年6月我院收治的早期宫外孕疑似病例108例进行分析,先使用B超、容积对比成像-C平面、断层超声成像技术对患者进行检查并存档,然后空腹采集患者静脉血并使用全自动血液分析仪检测其血清中的孕酮、β-HCG及CA125水平。结果:共102例患者确认为宫外孕且为输卵管内妊娠,3例卵巢妊娠,经彩色超声波检查准确率达97.22%。宫外孕患者子宫内膜血流RI及子宫内膜厚度与其他患者比较差异有统计学意义(P<0.05);3例患者虽然出现黄体破裂包块,但与宫外孕患者血流频谱形态差异具有统计学意义(P<0.05);宫外孕组患者血清中孕酮、β-HCG及CA125水平均明显低于黄体破裂组,其差异具有统计学意义(t=4.607,P=0.044;t=6.980,P=0.020;t=5.407,P=0.033)。结论:采用经阴道及经腹超声并结合血清学检测指标联合诊断宫外孕时,其临床准确率较高,具有较高的临床意义。
Objective: To analyze the clinical accuracy and clinical significance of transvaginal and transabdominal ultrasonography combined with serum markers in the diagnosis of ectopic pregnancy, and provide the basis for clinical promotion. Methods: From June 2012 to June 2015, 108 cases of early ectopic pregnancy treated in our hospital were analyzed. The patients were inspected and archived by B-contrast, volume contrast imaging-C plane and tomographic imaging, and then fasting Patients’ venous blood was collected and serum progesterone, β-HCG and CA125 levels were measured using a fully automated hematology analyzer. Results: A total of 102 patients were confirmed as ectopic pregnancy and oviduct pregnancy, 3 cases of ovarian pregnancy, the color ultrasound accuracy of 97.22%. Endometrial blood flow RI and endometrial thickness in patients with ectopic pregnancy were significantly different from other patients (P <0.05). Although three patients had ruptured corpus luteum, the differences of blood flow patterns between patients with ectopic pregnancy and those with ectopic pregnancy were statistically significant (P <0.05). The levels of serum progesterone, β-HCG and CA125 in ectopic pregnancy group were significantly lower than those in luteal rupture group (t = 4.607, P = 0.044; 0.020; t = 5.407, P = 0.033). Conclusion: The combination of transvaginal and transabdominal ultrasonography combined with serological markers in the diagnosis of ectopic pregnancy, the clinical accuracy rate is high, with high clinical significance.