论文部分内容阅读
目的:对颅高压中低频成分进行频谱分析,发现存在一种频率为0.1～0.2Hz的波动,记为M波。初步探讨M波的产生条件和变化规律,并采用药物干预研究分析其影响因素。方法:5条实验犬安置硬膜外球囊并注液制成颅高压模型。在颅内压升高过程中,采用频谱分析颅压波动;一旦发现出现M波,则分别予以副交感神经阻断剂阿托品,普萘洛尔及甘露醇干预,并观察M波变化。结果:M波多在颅压水平较高及颅压升高后阶段出现,可以被阿托品抑制。结论:M波可能是机体在颅高压状态下,由副交感神经系统反射而产生的反应,其持续存在提示预后不良。
OBJECTIVE: To analyze the spectrum of middle and low frequency components of intracranial hypertension and find that there is a fluctuation of 0.1 ~ 0.2Hz, which is recorded as M wave. Preliminary discussion of M wave generation conditions and changes in law, and the use of drug intervention study to analyze its influencing factors. Methods: Five experimental dogs were placed epidural balloon and injected into the model of intracranial hypertension. In the process of increasing intracranial pressure, frequency spectrum analysis of intracranial pressure fluctuations; once the occurrence of M wave, were respectively parasympathetic nerve blockers atropine, propranolol and mannitol intervention, and observed M wave changes. Results: M wave more in the high intracranial pressure and intracranial pressure after the stage, can be atropine inhibition. Conclusion: M wave may be the body’s response to parasympathetic reflex in the condition of intracranial hypertension. The persistence of M wave suggests a poor prognosis.