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目的 :探寻安全、方便、快速、可靠的预防剖宫产产后 2小时 (第四产程 )出血的方法 ,本研究观察米索前列醇宫腔放置预防剖宫产第四产程产后出血的效果。方法 :选择 36 6例剖宫产病例 ,随机分为米索前列醇 +催产素组 (简称米索组 )和催产素组 ,米索组 132例 ;胎儿娩出后宫体注射催产素 2 0U ,胎盘、胎膜娩出后宫腔放置米索 2 0 0 μg ;催产素组 2 34例 ;胎儿娩出后宫体注射催产素 2 0U ,再静脉滴注催产素 2 0U ,以上两组观察第四产程的出血量。结果 :第四产程平均出血量 :米索组为 (80 .1± 31.3)ml,催产素组为 (14 0± 80 .7)ml ,两组比较差异性极显著 (P <0 .0 1)。结论 :米索前列醇能较好地预防剖宫产术后第四产程的出血 ,且用药安全、方便、快速、有效
Objective: To explore a safe, convenient, rapid and reliable method to prevent bleeding after 2 hours (fourth stage) cesarean section. This study was to observe the effect of misoprostol placed in the uterine cavity to prevent postpartum hemorrhage in the fourth stage of cesarean section. Methods: A total of 366 cases of cesarean section were selected and randomly divided into misoprostol + oxytocin group (group misoprostol) and oxytocin group, 132 cases of misoprostol group. The fetus was injected with 20 U oxytocin , Fetal membranes were placed after delivery of misoprostol 200 ug; oxytocin group of 34 cases; the fetus was delivered after the hysterical injection of oxytocin 20U, and then intravenous infusion of oxytocin 20U, the above two groups to observe the fourth stage of the amount of bleeding . Results: The average amount of bleeding during the fourth stage of labor was (80.1 ± 31.3) ml in the misoprostol group and (14 ± 80.7) ml in the oxytocin group, with significant difference between the two groups (P <0.01) ). Conclusion: Misoprostol can prevent bleeding during the fourth stage of labor after cesarean section, and it is safe, convenient, rapid and effective