目的:制备维生素C阴道分散片,考察其溶出度及稳定性影响因素。方法:以崩解时限为指标,采用正交试验法对维生素C分散片处方进行筛选。测定并与普通片比较其体外溶出度。结果:维生素C阴道分散片工艺简单、稳定性良好,在90s内全部崩解,符合分散片的质量标准。结论:本品达到分散片要求、制剂质量稳定、体外溶出度明显优于普通片。 Objective: To prepare Vitamin C vaginal dispersible tablets and investigate the influencing factors of dissolution and stability. Methods: Taking the disintegration time as an index, the prescription of vitamin C dispersible tablets was screened by orthogonal test. Determination and compared with ordinary tablets in vitro dissolution. Results: Vitamin C vaginal dispersible tablets process is simple, good stability, all within 90s disintegration, in line with the quality standards of dispersible tablets. Conclusion: This product meets the requirements of dispersible tablets, the preparation of stable quality, in vitro dissolution was significantly better than ordinary tablets.