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目的:观察凉血止痢汤与锡类散保留灌肠治疗溃疡性结肠炎的疗效。方法:选取80例溃疡性结肠炎患者,按随机数字表法分为两组,对照组(39例)给予锡类散治疗,观察组给予凉血止痢汤治疗,观察两组治疗后的疗效,腹痛、腹泻、脓血便消失时间,治疗前后C反应蛋白、白细胞、血红蛋白数目及治疗期间不良反应情况。结果:治疗后,两组治疗有效率比较无明显差别(P>0.05),观察组患者腹痛、腹泻、脓血便消失时间均短于对照组(P<0.05),两组组白细胞数目、C反应蛋白水平均较治疗前显著下降且观察组上述指标较对照组更低(P<0.05)。两组血红蛋白数目均较治疗前显著上升且观察组较对照组更高(P<0.05)。两组治疗期间均无肝肾功能异常、胃肠道异常等不良反应发生。结论:凉血止痢汤与锡类散联合对溃疡性结肠炎均具有较好的治疗效果,能更快消退溃疡性结肠炎症状,且安全性高。
Objective: To observe the curative effect of Liangxueshizhi Decoction and tin-type retention enema on ulcerative colitis. Methods: Eighty ulcerative colitis patients were selected and divided into two groups according to the random number table. The control group (39 cases) was treated with tin scattered therapy. The observation group was treated with Liangxueshizhi Decoction. The therapeutic effects of the two groups were observed , Abdominal pain, diarrhea, disappearance of pus and blood, the number of C-reactive protein, white blood cells and hemoglobin before and after treatment, and the adverse reactions during treatment. Results: After treatment, there was no significant difference between the two groups (P> 0.05). The disappearance time of abdominal pain, diarrhea and pus and blood in the observation group were shorter than that of the control group (P <0.05) Protein levels were significantly lower than before treatment and the observation group than the control group indicators lower (P lt; 0.05). The number of hemoglobin in both groups was significantly higher than that before treatment and the observation group was higher than the control group (P <0.05). No liver and kidney dysfunction, gastrointestinal abnormalities and other adverse reactions occurred during the two groups. Conclusion: Liangxueshilizhi Decoction combined with tin powder has good curative effect on ulcerative colitis, and can quickly relieve the symptoms of ulcerative colitis with high safety.