论文部分内容阅读
目的评估无创性正压通气(NIPPV)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的临床疗效。方法将河南省延津县人民医院住院的154例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的患者纳入研究对象中,随机分为两组,对照组与正压通气组,每组各77例,前者予常规治疗,后者予常规加NIPPV治疗。治疗前后均密切监测患者的生命体征及动脉血气的改变。结果试验组中有3例患者因不能耐受NIPPV而退出试验。通气治疗后3h、12h和48h的动脉血气结果改善情况均优于对照组。结论 NIPPV对于COPD合并Ⅱ型呼衰的患者疗效较为肯定,在无禁忌证的情况下可优先选择。
Objective To evaluate the clinical efficacy of noninvasive positive pressure ventilation (NIPPV) in the treatment of chronic obstructive pulmonary disease (COPD) with type Ⅱ respiratory failure. Methods A total of 154 patients with chronic obstructive pulmonary disease and type Ⅱ respiratory failure hospitalized in Yanjin People’s Hospital of Henan Province were included in the study. They were randomly divided into two groups: control group and positive pressure ventilation group, with 77 cases in each group. The former to conventional treatment, the latter to conventional plus NIPPV treatment. Before and after treatment were closely monitored in patients with vital signs and arterial blood gas changes. Results Three patients in the experimental group withdrew from the trial because they could not tolerate NIPPV. The improvement of arterial blood gas at 3h, 12h and 48h after ventilation was better than that of the control group. Conclusion NIPPV is more effective in COPD patients with type Ⅱ respiratory failure, and may be given priority in the absence of contraindications.