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目的:为了解海北州部分健康人群百日咳,白喉和破伤风的免疫状况,评价百白破三联试剂(DPT)的效果。方法:用酶联免疫吸附实验测定百日咳,白喉,破伤风lgG抗体,随机抽取0岁~,2岁~,4岁~,6岁~,8岁~健康人群150人。结果:百日咳抗体阳性率80.0%(120/150);白喉抗体阳性率77.3%(116/150);破伤风抗体阳性率80.0%。结论:海北州部分健康人群百日咳、白喉、破伤风抗体保护率比较低,提示我们要扩大接种覆盖率,提高冷链运转效率和疫苗接种质量。
OBJECTIVE: To evaluate the immune status of pertussis, diphtheria and tetanus in some healthy people in Haibei prefecture and to evaluate the efficacy of DPT. Methods: Pertussis, diphtheria and tetanus IgG were detected by enzyme - linked immunosorbent assay. 150 healthy people from 0 to 2 years old to 4 years old to 6 years old to 8 years old were randomly selected. Results: The positive rate of pertussis antibody was 80.0% (120/150). The positive rate of diphtheria antibody was 77.3% (116/150). The positive rate of tetanus antibody was 80.0%. Conclusion: The protective rates of pertussis, diphtheria and tetanus antibodies in some healthy people in Haibei Prefecture are relatively low, suggesting that we should expand vaccination coverage and improve cold chain operation efficiency and vaccination quality.