膀胱癌是环境因素、职业、生活习惯等多因素共同作用的多因性疾病。近年大量研究资料表明,膀胱癌易发生非随机的染色体改变,包括结构畸变和染色体数目的异常,导致细胞慢性增殖,最后形成癌。本文介绍了目前与膀胱癌发生、进展密切相关的3、7、9、17号等染色体改变的研究现状。 Bladder cancer is a multifactorial disease with environmental factors, occupations, living habits and other factors. In recent years, a large number of research data show that bladder cancer prone to non-random chromosomal changes, including structural aberrations and chromosomal abnormalities, leading to chronic cell proliferation, the final formation of cancer. This article describes the present and the progress of bladder cancer, 3,7,9,17 closely related to the status quo of chromosome changes.