论文部分内容阅读
目的:观察益气养精法中药配合化疗治疗精气两亏型老年晚期非小细胞肺癌(NSCLC)患者的临床疗效。方法:对99例患者采用随机、对照研究方法分为2组,治疗组51例,对照组48例。2组患者化疗均采用NP方案,治疗组在化疗期间加服益气养精、健脾和胃的抗瘤增效方,化疗结束后长期口服益气养精、解毒散结为主的肺岩宁方。治疗28天为1疗程,至少接受2疗程治疗。观察2组生存期、近期疗效、症状改善、KPS评分、体重的变化。结果:治疗后中位生存期对照组为(389±29.69)天,治疗组为(467±61.28)天,2组比较,差异无显著性意义(P>0.05),但治疗组稍高于对照组。治疗组KPS评分、体重、证候积分改善均优于对照组,2组比较,差异均有非常显著性意义(P<0.01),显示治疗组患者的生活质量在治疗过程中和治疗后均优于对照组。结论:益气养精法中药配合化疗治疗精气两亏型老年晚期NSCLC患者在一定程度上可以提高临床疗效,改善患者生活质量,延长生存期。
Objective: To observe the clinical effects of Yiqi Yangjing method combined with chemotherapy in the treatment of Jingqi two-deficient elderly patients with advanced non-small cell lung cancer (NSCLC). Methods: Ninety-nine patients were divided into two groups according to a randomized, controlled study: 51 cases in the treatment group and 48 cases in the control group. Two groups of patients with chemotherapy were used NP regimen, the treatment group during the chemotherapy plus service qi and nourishing essence, spleen and stomach antitumor efficacy side, long-term oral chemotherapy after the end of chemotherapy enriching, detoxification Sanjie dominated lung rock Ning Fang. Treatment for 28 days for a course of treatment, at least 2 courses of treatment. The survival, the short-term curative effect, the improvement of symptoms, KPS score and body weight were observed in two groups. Results: The median survival time was (389 ± 29.69) days in treatment group and (467 ± 61.28) days in treatment group. There was no significant difference between the two groups (P> 0.05), but the treatment group was slightly higher than the control group group. The improvement of KPS score, body weight and syndrome score of the treatment group were better than that of the control group. There was significant difference between the two groups (P <0.01), which showed that the quality of life in the treatment group was better during and after treatment In the control group. Conclusion: Yiqi Yangjing method combined with chemotherapy in the treatment of Jingqi two-deficient elderly patients with advanced NSCLC can improve clinical efficacy to some extent, improve the quality of life of patients and prolong the survival period.