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目的以B、C基因型为主的我国隐匿性乙型肝炎病毒感染(OBI)的流行病学调查与分子生物学特性分析还没有详尽的研究报道。方法收集深圳市血液中心健康献血者中的隐匿性乙型肝炎病毒感染样品,经规律跟踪检测,采用巢式聚合酶链反应(Nested-PCR)扩增标本中HBV BCP/PC、Pre-S/S基因片
Objective To investigate the epidemiological investigation and molecular biological characteristics of occult hepatitis B virus (OBI) in China based on genotypes B and C. It has not been reported yet. Methods Samples of occult hepatitis B virus (HBV) infection in blood donors from Shenzhen Blood Center were collected and tested by regular follow-up. Nested-PCR was used to amplify HBV BCP / PC and Pre-S / S gene fragment