慢性粒细胞白血病(CML)是起源于多能干细胞的克隆增殖性疾病,CML发病是由于导致异常增高的酪氨酸激酶活性的BCR-ABL融合基因所致。近年来,CML有许多治疗方法可以选择,异基因或同基因造血干细胞移植是治疗CML的有效手段,能够获得长期无病生存,但复发率和死亡率都较高。近年来,采 Chronic myelogenous leukemia (CML) is a clonal proliferative disease that originates from pluripotent stem cells. The onset of CML is due to the BCR-ABL fusion gene that results in abnormally increased tyrosine kinase activity. In recent years, CML has many treatments to choose from. Allogeneic or allogeneic hematopoietic stem cell transplantation is an effective treatment for CML and can achieve long-term disease-free survival with high relapse and mortality rates. In recent years, mining