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目的探讨慢性肾功能不全患者病程发展过程中血清尿素氮(Bun)及血清肌酐(Cr)、钙(Ca2+)、磷(P3-)的变化及其关系。方法选择458例慢性肾功能不全患者,检测其血清尿素氮(BUN)及血清肌酐(Cr)、钙(Ca2+)、磷(P3-)等指标的水平。结果在被检慢性肾功能不全患者中:检验指标异常者159人,占总人数的34.72%,其中Bun升高67人(占14.62%)、Cr升高37人(占8.07%)、Ca2+升高7人(占1.53%)、Ca2+降低14人(占3.6%)、P3-升高38人(占8.3%)。慢性肾功能不全患者血清中各项指标随病情变化而变化。结论慢性肾功能不全患者,早期血清中钙、磷水平无明显改变,随着血清尿素氮、肌酐水平的提高,血钙、磷水平才有显著变化。
Objective To investigate the changes of serum urea nitrogen (Bun), serum creatinine (Cr), calcium (Ca2 +) and phosphorus (P3-) in patients with chronic renal failure during their course of disease. Methods 458 patients with chronic renal failure were enrolled in this study. Serum urea nitrogen (BUN), serum creatinine (Cr), calcium (Ca2 +) and phosphorus (P3-) were measured. Results Among the patients with chronic renal insufficiency (CHD), 159 were abnormal in test indicators, accounting for 34.72% of the total. Among them Bun increased by 67 (14.62%), Cr increased by 37 (8.07%), Ca2 + Seven (1.53%) were higher, 14 (3.6%) were reduced by Ca2 + and 38 (P3-) by 8.3%. Serum in patients with chronic renal insufficiency changes with the changes in the indicators. Conclusions In patients with chronic renal insufficiency, there is no significant change in early serum calcium and phosphorus levels. With the increase of serum urea nitrogen and creatinine levels, there is a significant change in serum calcium and phosphorus levels.