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目的探讨并分析本院抗生素临床应用情况。方法对本院就诊感染患者1800例进行回顾分析。结果本院1800例患者抗生素应用后临床转归分析,其中治疗后临床治愈1720例,占94%,80例患者在经过抗生素治疗后效果差。结论临床医师应根据感染病原菌特点及细菌药敏结果选用药物,药敏试验虽是体外试验,但它是作为预测抗生素对细菌是否有效的指标,可为合理选用抗生素提供客观依据。因此应重视病原学检查,依据药敏结果合理选用抗生素,以减少耐药菌株产生及盲目使用抗生素。各类抗菌药物的药效学和人体药动力学特点不同,临床医师应根据各种抗菌药物的不同特点,及不同的适应征,正确选用抗菌药物。
Objective To investigate and analyze the clinical application of antibiotics in our hospital. Methods A retrospective analysis of 1,800 infected patients in our hospital was conducted. Results 1800 patients in our hospital after the application of antibiotic clinical outcome analysis, of which 1720 cases of clinical cure after treatment, accounting for 94%, 80 patients after antibiotic treatment is poor. Conclusion Clinicians should choose drugs according to the characteristics of pathogenic bacteria and drug susceptibility of bacteria. Although drug susceptibility test is an in vitro test, it is an indicator to predict the effectiveness of antibiotics on bacteria and provide an objective basis for the rational selection of antibiotics. Therefore, attention should be paid to etiological examination, rational selection of antibiotics based on susceptibility results to reduce the generation of resistant strains and the blind use of antibiotics. Various types of antibacterial pharmacodynamics and human pharmacokinetic characteristics are different, clinicians should be based on the different characteristics of various antibacterial drugs, and different indications, the correct choice of antimicrobial agents.