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目的探讨米力农(二联吡啶酮)治疗新生儿持续肺动脉高压的疗效。方法选取2009年12月～2011年12月本院收治的新生儿持续肺动脉高压患者84例,随机分为观察组42例,对照组42例,对照组进行常规治疗,观察组在常规治疗的基础上给予米力农进行治疗。比较两组患者的临床疗效。结果对照组疗效优良率78.57%明显低于观察组优良率97.62%,两组患者在临床疗效优良率上有显著性差异,(χ2=11.08,P<0.05),具有统计学意义。结论在常规治疗的基础上联合使用米力农进行雾化吸入治疗新生儿持续肺动脉高压具有确切的临床疗效,值得临床推广使用。
Objective To investigate the efficacy of milrinone (dipyridone) in the treatment of persistent pulmonary hypertension in newborns. Methods Eighty-four neonates with persistent pulmonary hypertension admitted from December 2009 to December 2011 in our hospital were randomly divided into observation group (n = 42), control group (n = 42) and control group. The control group received routine treatment Give Milinong treatment. The clinical efficacy of the two groups was compared. Results The excellent and good rate of 78.57% in the control group was significantly lower than that in the observation group (97.62%). There was significant difference between the two groups in the excellent clinical efficacy rate (χ2 = 11.08, P <0.05), with statistical significance. Conclusion Based on the conventional treatment, the combined use of milrinone inhalation for the treatment of persistent pulmonary hypertension in neonates has a definite clinical effect and is worthy of clinical application.