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为探讨微血管在正常宫颈组织和宫颈鳞癌中的状况，采用免疫组化ＬＳＡＢ法对８０例宫颈鳞癌和１５例正常宫颈组织中的微血管数进行了检测。结果显示：①正常宫颈组织中微血管数明显低于宫颈鳞癌；②微血管数与宫颈鳞癌临床分期呈正相关（在２００倍显微镜视野下：Ⅰｂ期为１４．５１±６．５１根，Ⅱ期为１９．８４±４．７３根，Ⅲ期为３２．２６±６．８２根），与外生型肿瘤的菜花直径大小有关（在２００倍显微镜视野下：直径≤４ｃｍ，ＭＶＣ＝１８．０８±７．５６根；直径＞４ｃｍ，ＭＶＣ＝２３．９１±８．０５根），与淋巴结转移状况有关（ＬＰＧ＋，ＭＶＣ＝２４．１３±９．８３根；ＬＰＧ－，ＭＶＣ＝１８．５４±５．９９根），均Ｐ＜０．０５，且在２００倍显微镜下每增加５根血管，肿瘤发生淋巴结转移的机会将增加１．６１倍，而与组织学分级无关。结果提示：微血管计数能够反映宫颈癌的恶性潜能，是观察宫颈癌预后的重要指标。
To investigate the status of microvessel in normal cervical tissue and cervical squamous cell carcinoma, the number of microvessels in 80 cases of cervical squamous cell carcinoma and 15 cases of normal cervical tissue was detected by immunohistochemical LSAB method. The results showed that: ① The number of microvessels in normal cervical tissue was significantly lower than that in cervical squamous cell carcinoma; ② The number of microvessel was positively correlated with the clinical stage of cervical squamous cell carcinoma (under the microscope of 200 times: Ⅰb was 14.51 ± 6.51, 19.84 ± 4.73, and stage Ⅲ was 32.26 ± 6.82), which was related to the diameter of cauliflower of exophytic tumor (200 × microscope field: diameter≤4cm, MVC = 18.08 ± 7.56; diameter> 4cm, MVC = 23.91 ± 8.05), and lymph node metastasis (LPG +, MVC = 24.13 ± 9.83; LPG-, MVC = 18.54 ± 5.99), all P <0.05, and for every additional 5 vessels under 200 times microscope, the chances of lymph node metastasis of tumor increased by 1.61 times, but not with histological grade. The results suggest that microvessel count can reflect the malignant potential of cervical cancer and is an important indicator to observe the prognosis of cervical cancer.