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舞蹈病是伴发于多种神经系统疾病的一个综合征。过去曾用吩噻嗪类、丁酰苯类、利血平及一些镇静剂作为症状性治疗,取得了不同程度的疗效。三氟拉嗪系哌嗪的衍生物,是一种广泛用于治疗精神病的药物。在应用中,较常出现巴金森氏综合征的副作用。根据运动异常发病机理的现代概念“舞蹈病与巴金森氏综合征是一种相对立的疾病”,所以三氟拉嗪有可能用于舞蹈病的治疗,过去在文献上曾有过报导。接受本药治疗者10例,其中遗传性舞蹈病4例,小舞蹈病3例,血管病变或病因未定者3例。按病情本组病例又分为(1)轻度:系指影响患者的运动
Chorea is a syndrome associated with various neurological diseases. In the past with phenothiazines, butyrophenones, reserpine and some sedatives as a symptomatic treatment, achieved varying degrees of efficacy. Trifluoperazine piperazine derivatives, is a widely used drug for the treatment of mental illness. In applications, the side effects of Parkinson’s disease are more common. According to the modern concept of the pathogenesis of dyskinesia, “chorea is a relative disease with Parkinson’s syndrome,” it is possible that trifluoperazine may be used in the treatment of chorea and has been reported in the literature. Ten patients received the drug treatment, including hereditary chorea in 4 cases, 3 cases of small chorea, vascular disease or etiology in 3 cases. According to the condition of this group of patients is divided into (1) Mild: refers to the impact of patient movement