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为了提高胶质瘤化疗的疗效 ,我们研制了卡氮芥聚乳酸缓释剂 (ＢＣＮＵ ＰＬＡ) ,并曾初步探讨了其体外释放特性。本研究进一步对ＢＣＮＵ ＰＬＡ对大鼠体重和血细胞的影响 ,还将ＢＣＮＵ ＰＬＡ用于治疗大鼠脑胶质瘤 ,收到良好疗效。一、材料与方法1 .ＢＣＮＵ ＰＬＡ缓释剂对
In order to improve the efficacy of glioma chemotherapy, we developed BCNU PLA sustained-release agent (BCNU PLA), and preliminary study of its in vitro release characteristics. This study further on the impact of BCNU PLA on body weight and blood cells in rats, BCNU PLA will also be used to treat rat glioma, received good effect. First, materials and methods 1 .BCNU PLA sustained release agent