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目的动态分析38年来乳腺癌手术临床流行病学的特征变迁。方法用我院1970年~2007年乳腺癌住院病例622例分析,按4个年段进行统计,了解乳腺癌外科治疗发展情况。结果乳腺癌病例数明显上升,发病年龄高峰前移,中位发病年龄从1970年的56.0岁下降到2007年的49.0岁;青年人患病率从20世纪70年代的5.3%上升到2000年后的22.3%(P<0.05);老年人患病率从上世纪70年代的23.7%下降到2000年后的9.8%(P<0.01);>4cm肿瘤在20世纪70年代占34.2%,2000年后占31.1%(P<0.05)。腋淋巴结转移率在上世纪70年代占81.6%,90年代后占69.1%(P>0.05)。结论乳腺癌发病呈明显上升的趋势,青年人发病上升,发病年龄高峰前移,但中、晚期肿瘤格局无改变。传统根治术比例下降,改良根治术上升。
Objective To dynamically analyze the clinical epidemiological characteristics of breast cancer surgery over the past 38 years. Methods The hospitalized patients with breast cancer in our hospital from 1970 to 2007 were analyzed in 622 cases. The statistics were made according to the four years to understand the development of surgical treatment of breast cancer. Results The number of cases of breast cancer increased significantly, the peak age of onset was shifted forward, and the median age of onset decreased from 56.0 years in 1970 to 49.0 years in 2007; the prevalence of young people increased from 5.3% in the 1970s to 2000 (P <0.05). The prevalence of the elderly decreased from 23.7% in the 1970s to 9.8% after 2000 (P <0.01). The tumors with> 4 cm in the 1970s accounted for 34.2% Accounting for 31.1% (P <0.05). Axillary lymph node metastasis rates accounted for 81.6% in the 1970s and 69.1% after the 1990s (P> 0.05). Conclusion The incidence of breast cancer showed a clear upward trend, the incidence of young people increased, the age of onset peak forward, but no change in the pattern of the middle and late tumors. The proportion of traditional radical surgery decreased, improved radical mastectomy.