研究转筋草Pachysandra terminalis化学成分。综合运用硅胶柱色谱、凝胶柱色谱、制备HPLC色谱等分离色谱法分离纯化转筋草中的化学成分,采用NMR和质谱等有机波谱学方法鉴定各单体化合物的结构。从转筋草中分离得到5个化合物,鉴定为2-甲基-3-亚甲基-1,2,5-戊三醇(1),4-甲基-3-亚甲基-1,2,5-戊三醇(2),4-甲基-3-亚甲基-1,2,5-戊三醇-5-O-β-D-吡喃葡萄糖苷(3),4-甲基-3-亚甲基-1,2,5-戊三醇-1-O-β-D-吡喃葡萄糖苷(4),(7S,8R,8’R)-(+)-落叶松醇-9-O-β-D-吡喃葡萄糖苷(5)。其中化合物1～4为新化合物,化合物5为首次从该植物中分离得到。 Study on the chemical constituents of Pachysandra terminalis. The constituents were isolated and purified by silica gel column chromatography, gel column chromatography and preparative HPLC. The structures of the compounds were identified by NMR and mass spectrometry. Five compounds were isolated from the turnip grass and identified as 2-methyl-3-methylene-1,2,5-pentanetriol (1), 4-methyl-3-methylene- Pentanetriol (2), 4-methyl-3-methylene-1,2,5-pentanetriol-5-O-β-D-glucopyranoside (3), 4- Methyl-3-methylene-1,2,5-pentanetriol-1-O-β-D-glucopyranoside (4), (7S, 8R, 8’R) Pinacol-9-O-β-D-glucopyranoside (5). Compounds 1 ~ 4 were new compounds, and compound 5 was isolated from this plant for the first time.