论文部分内容阅读
报道具有强心活性的化合物４，５－二氢－５－甲基－６－［４－［（２－甲基－３－氧代－１－环戊烯基）氨基］苯基］－３（２Ｈ）－哒嗪酮（ＮＳＰ－８０５）的合成。并进行了体外血小板聚集抑制试验，发现它有很强的活性，ＩＣ５０为０．４３ μｍ ｏｌ／Ｌ。
Reported that a compound having a cardiac activity 4,5-dihydro-5-methyl-6- [4 - [(2-methyl-3- oxo- 1 -cyclopentenyl) amino] phenyl] (2H) -pyridazinone (NSP-805). And in vitro platelet aggregation inhibition test and found that it has strong activity, IC50 0.43 μm ol / L.