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本文应用蚕豆根尖微核技术对广西大厂锡矿区工作面采集的11份矿尘样品进行了致突变性检测。结果:矿尘样微核率(14.7～19.9‰)明显高于对照组(P<0.01);对其中45号矿尘样进行了剂量—效应试验,结果呈明显的剂量—效应关系。提示矿尘具有致突变活性,可能是导致大厂锡矿工人肺癌高发的原因之一。为此,加强防尘措施,降低环境矿尘浓度,可能对减少该矿肺癌发病具有重要意义。
In this paper, Vicia faba root tip micronucleus technology was used to detect the mutagenicity of 11 samples of mine dust collected from the working face of Dachang tin mining area in Guangxi province. Results: The micronucleus frequency (14.7 ~ 19.9 ‰) was significantly higher than that of the control group (P <0.01). The dose-effect test was carried out on No.45 mine dust and the results showed a significant dose-effect relationship. Tip mine dust mutagenic activity may be caused by the large Tin workers tin mine one of the reasons for the high incidence of lung cancer. To this end, strengthening dust control measures to reduce the concentration of environmental dust, may reduce the incidence of lung cancer in this mine is of great significance.