论文部分内容阅读
本文报道用单克隆抗体D9B1(mcAbD9B1)研究了宫内节育器(IUD)对内膜分泌活性的影响。 38例宫内膜标本取自21～51岁放置IUD的行经妇女,其中36例放置Cu IUD 8周～8年,2例置惰性IUD 5和17年。除2例为未产妇外,其余均为经产妇,有一个以上孩子。取内膜的指征为:①宫颈疾病11例,包括上皮内肿瘤9例、宫颈息肉2例;②绝育10例;③计划避孕8例;④月经紊乱9例,包括月经过多和月经间期出血者。因此本研究中29例内膜并无与IUD有关的临床问题。33例月经规则者中31例周期为23～33天,另2例分别为21和42天;5例月经不规则,周期为10～42天。取出的内膜固定、切片后,一份供病理组织学检查,另一份用mcAbD9B1作间接过氧物酶染色,供免疫组织
This article reports the use of monoclonal antibody D9B1 (mcAbD9B1) to study the effect of intrauterine device (IUD) on endometrial secretion. 38 cases of endometrial specimens taken from 21 to 51 years old women with IUD placement, of which 36 cases placed Cu IUD for 8 weeks to 8 years, 2 patients with inert IUD 5 and 17 years. In addition to 2 cases of non-mothers, the rest are mothers, more than one child. Indications of endometrial taken: ① 11 cases of cervical disease, including 9 cases of intraepithelial neoplasia, cervical polyps in 2 cases; ② 10 cases of sterilization; ③ planned contraception in 8 cases; ④ menstrual disorders in 9 cases, including menorrhagia and menstrual period Period of bleeding. Therefore, in this study, 29 cases of endometrium and IUD-related clinical problems. 33 cases of menstrual rules in 31 cases of period of 23 to 33 days, the other two cases were 21 and 42 days; 5 cases of irregular menstruation, the period of 10 to 42 days. Remove the endometrial fixed, after slicing, a for pathological examination, the other with mcAbD9B1 for indirect peroxidase staining for immunohistochemistry