本文对25例男性不育症患者的睾丸活检组织进行了超微结构观察。结果表明不育症患者睾丸曲细精管界膜有显著变化,主要为界膜增厚、界膜纤维化、基膜样物质沉积、肌样细胞变性及肥大细胞增多。间质中可见结缔组织增生或小血管内皮细胞肿胀。支持细胞有空泡变性,支持细胞综合症患者的支持细胞呈未成熟型,支持细胞间未形成复合连接,而在其它病例,则有血睾屏障存在。 In this paper, 25 cases of male infertility testis biopsies were observed ultrastructure. The results show that in infertility patients testicular seminiferous tubules have significant changes in the regulatory film, mainly for the thickening of the boundary membrane, membranous fibrosis, basement membrane-like substance deposition, myoid cell degeneration and mast cells increased. Interstitial hyperplasia of connective tissue or small blood vessel endothelial cell swelling. Support cells have vacuolar degeneration, supporting cells of patients with cell syndrome was immature, supporting cells did not form a complex connection, and in other cases, there is blood testis barrier exists.