p53 MUTATIONS AND PROTEIN OVEREXPRESSION IN PRIMARY COLORECTAL CANCER AND ITS LIVER METASTASIS

来源 :中国癌症研究:英文版 | 被引量 : 0次 | 上传用户:hwen1023
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客观:在 34 个病人在主要、肝的变形 colorectal 癌症比较 p53 地位。方法:p53 基因地位(exons 5 鈥 ?) 被 PCR 检验,使中毒的坡度胶化电气泳动(DGGE ) 并且定序自动化。P53 蛋白质被 immunohistochemistry 用 monoclonal 抗体 DO-7 检测。结果:p53 变化在 exons 被发现 5 通过 9 在 34 个病人(61.8%) 中的 21 个。在他们之中,当在另外的病人一样的变化在主要、变形的 colorectal 癌症被发现时,
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