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目的总结应用调Q紫翠玉宝石激光(755nm)联合CO2激光治疗面部脂溢性角化病疗效。方法随访于2011至2012年间在如皋市人民医院经过调Q紫翠玉宝石激光联合CO2激光治疗面部脂溢性角化病患者。结果随访完成治疗的患者149例，年龄从45至85岁(平均为67.4岁)，随访时间由6个月至12个月(平均9.3个月)所有患者治疗1至3次治疗程度如下：痊愈68例(56.2%)，显著改善29例(24%)，好转14例(11.6%)和无变化或轻度改善10(8.2%)，总有效率80.2%治疗发现副作用如色素沉着，伤痕。结论调Q紫翠玉宝石激光(755nm)联合CO2激光治疗面部脂溢性角化病疗效好，安全性高。“,” Objective To observe the clinical effect in the treatment of the seborrheic keratosis by using the Q-switched Alexandrite laser and CO2 Laser.Methods According to the ages,sex and condition of diseases of 149 patients,these seborrheie keratosis patients were treated through choosing the different technical parameters.Results In the 149 patients,the numbers of male and female were 54 and 95,respectively.Their ages ranged from 45 to 85,and the average age Was 67.4.The suffering time ranged from 0.5 year to 2 years ago.Al the patients were treated 1 to 3 times.The degrees of the clearing were as fol ows:complete clearing 68 cases(56.2%),significant improvement 29 cases(24%),moderate im-provement 14(11.6%)and no change or mild improvement 10(8.2%).The tolal effective rate was 80.2%.Side effects such as hyperpigmentation and scars,were not found.Conclusions The use of Q-switched Alexandrite laser and CO2 Laser is a safe and effective method for treatment of seborrheic keratosis.