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目的 观察息肉状脉络膜血管病变 (PCV)的病程变化及视力预后。 方法 对 15例临床确诊的 PCV患者的 2 0只患眼行矫正视力和眼底彩色照相随访观察 ,随访时间 2～ 6 4个月 ,平均随访时间19.1个月 ;其中 10例 14只眼采用荧光素眼底血管造影 (FFA)和吲哚青绿血管造影 (ICGA)作了眼底形态学的随访 ,随访时间 3～ 5 3个月 ,平均随访时间 2 1.0个月。 结果 2 0只眼中随访视力为 0 .3及其以上者5只眼 ,占 2 5 .0 % ;视力为 0 .1～ 0 .2者 6只眼 ,占 30 .0 % ;视力为 0 .1以下者 9只眼 ,占 4 5 .0 %。随访过程中 2只眼视力增进 ,占 10 .0 % ;10只眼视力稳定 ,占 5 0 .0 % ;8只眼视力下降 ,占 4 0 .0 %。仅 1只眼形成盘状瘢痕 ,占 5 .0 %。 14只眼底血管造影随访的患眼中 ,造影显示息肉状病灶稳定不变者 4只眼 ,占 2 8.6 % ;部分消退者 2只眼 ,占 14 .3% ;有扩展和新生者 6只眼 ,占 4 2 .8% ;消退和新生并存者 2只眼 ,占 14 .3%。 结论 PCV患眼视力预后差异较大 ;在病程进展过程中息肉状病灶可增多、消退或稳定不变。
Objective To observe the course of polypoidal choroidal vasculopathy (PCV) and visual acuity prognosis. Methods Totally 20 eyes of 15 patients with PCV were retrospectively reviewed. The follow-up time ranged from 2 to 64 months and the average follow-up time was 19.1 months. Of the 10 cases, 14 eyes were treated with fluorescein Fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) were followed up for 3 ~ 53 months with a mean follow-up time of 1.02 months. Results 20 eyes were followed up for visual acuity of 0.3 or more and 5 eyes (25.0%), visual acuity was 0.1-2.2 (30.0%), and visual acuity was 0 (0%). 1 below 9 eyes, accounting for 4.5%. During the follow-up, visual acuity was improved in 2 eyes, accounting for 10.0%; visual acuity was stable in 10 eyes, accounting for 50.0%; visual acuity decreased in 8 eyes, accounting for 40.0%. Only 1 eye formed disc-shaped scar, accounting for 5.0%. Among the 14 eyes with angiographic follow-up, 4 eyes (28.6%) had stable polypoid lesions, 14 eyes (14.3%) had partial remission, 6 eyes had extended and newborn, Accounting for 42.8%; two patients with remission and freshmen coexisting, accounting for 14.3%. Conclusion The prognosis of PCV patients with different visual acuity is larger; in the course of disease progression of polypoid lesions can be increased, subsided or stable.