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目的评价先期动脉介入化疗栓塞及手术联合治疗中晚期宫颈癌疗效。方法对31例宫颈癌患者(Ⅱa期8例,Ⅱb期17例,Ⅲa期5例,Ⅲb期1例)术前介入性化疗栓塞后行广泛子宫切除术及盆腔淋巴结清扫术。结果近期疗效明显,术后病理淋巴转移率Ⅱ期为12%,Ⅲ期为66.67%。27人随访3年,存活23人,存活率达85.19%。结论先期介入性治疗能缩小肿瘤体积,降低淋巴结转移,提高手术切除率,联合手术治疗可明显提高患者生存率。
Objective To evaluate the efficacy of advanced arterial chemoembolization and surgery in the treatment of advanced cervical cancer. Methods Thirty-one patients with cervical cancer (8 in stage IIa, 17 in stage IIb, 5 in stage IIIa, and 1 in stage IIIb) underwent extensive hysterectomy and pelvic lymph node dissection after interventional chemoembolization. Results The short-term efficacy was obvious. Postoperative pathological lymph node metastasis rate was 12% in stage II and 66.67% in stage III. 27 patients were followed up for 3 years, 23 survived, and the survival rate was 85.19%. Conclusions Early interventional therapy can reduce the tumor volume, reduce the lymph node metastasis and improve the resection rate. Combined surgery can significantly improve the survival rate of patients.