目的探讨钳刮术前口服米索前列醇的临床效果。方法将100例自愿要求终止孕11~15w的健康妇女,随机分为两组每组各50例,一组钳刮术前1~2h口服米索前列醇600ug;另一组于钳刮术前1d宫颈管内插管,次日行钳刮术,比较两种方法的临床效果。结果钳刮术前口服米索前列醇可以有效的软化宫颈,使宫口自然扩张,较钳刮组避免和减轻了扩宫的机械性损伤及牵拉刺激,减轻了损伤,降低了受术者的痛苦及并发症的发生。结论钳刮术前口服米索前列醇安全、有效、可靠。值得临床推广。 Objective To investigate the clinical effect of oral misoprostol before forceps curettage. Methods 100 healthy women who volunteered to terminate pregnancy 11 ~ 15w were randomly divided into two groups of 50 patients in each group. One group was given oral misoprostol 600ug 1 ~ 2h before forceps curettage. The other group was treated with forceps 1d cervical intubation, the next day line clamp curettage, the clinical efficacy of the two methods. Results Before the curettage, oral administration of misoprostol could soften the cervix effectively and make the cervix natural expansion more than the clamp scraping group, which could avoid or reduce the mechanical damage and distraction of the dilated uterus, lessen the injury and reduce the risk of the affected The pain and complications occurred. Conclusion Oral misoprostol before forceps cure is safe, effective and reliable. Worth clinical promotion.