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临床怀疑干眼病综合征者,可由一系列试验证实诊断:1.定量分析试验,最常用的是Schirmer试验和虎红染色。2.定性试验,通过结膜的活体组织检查,显示杯状细胞稀少甚至消失。用带有钴兰色滤光片生物显微镜观察滴入荧光素后的泪液膜,在瞬目后,小的干燥区域出现的时间,若大于25秒,则认为泪液膜稳定性是正常的。3.泪腺的活体组织检查。本文31例睑部泪腺活体组织检查者均为泪腺分泌过少,Schirmer试验5分钟内少于5mm者,其中男性8例,女性23例,女性明显多于男性,年龄25-80岁。>60岁者居多。活体组织检查技术简单,取下泪腺组织后,做Masson三色染色检查。 Schirmer试验阳性、虎红染色明显的干燥性角结膜炎17例,单纯结膜炎10例,没有任何着
Clinical suspicion of dry eye syndrome, confirmed by a series of tests: 1. Quantitative analysis of the test, the most commonly used is the Schirmer test and tiger red staining. 2. qualitative test, through the conjunctival biopsy, goblet cell rare or even disappear. The tear film with fluorescein instillation was observed with a cobalt blue filter biomicroscope. After blinking, the appearance of a small dry area for more than 25 seconds was considered normal for tear film stability. 3. Lacrimal biopsy. In this paper, 31 cases of eyelid lacrimal gland biopsy were lacrimal gland secretion less than 5 minutes Schirmer test less than 5mm, of which 8 males and 23 females, significantly more women than men, aged 25-80 years. > 60-year-old are mostly. Biopsy technique is simple, remove the lacrimal gland tissue, do Masson trichrome staining. Schirmer test positive, tiger red staining obvious dry keratoconjunctivitis in 17 cases, simple conjunctivitis in 10 cases, there is no any