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本文观察环氧乙烷（ＥＴＯ）亚慢性吸入染毒小鼠（５４ｍｇ／ｍ３，３６Ｏｍｇ／ｍ３，２ｈ／ｄａｙ，６ｄ／Ｗｋ，／１４ｗｅｅｋ）骨髓细胞染色体结构畸变率显著高于正常对照组（４．２％Ｐ＜０．０１），５４ｍｇ／ｍ３染毒组未见显著性差异。此外，发现两组染毒小鼠骨髓细胞分裂相明显少于正常对照组，３６０ｍｇ／ｍ３浓度组细胞分裂抑制效应大于５４ｍｇ／ｍ３浓度组，细胞分裂受抑制的机理尚待探讨。
In this study, the chromosome aberrations of bone marrow cells in sub-chronic exposure to ETO (54mg / m3, 36Omg / m3, 2h / day, 6d / Wk, and 14week) were significantly higher than those in the normal control group .2% P <0.01), no significant difference was observed in 54mg / m3 exposure group. In addition, it was found that the division of bone marrow cells in the two groups was significantly less than that in the normal control group. The cell division inhibitory effect in 360mg / m3 concentration group was greater than 54mg / m3 concentration group. The mechanism of cell division inhibition was yet to be explored.