炎症性肠病一般是指以肠道炎症为主的疾病,特别是慢性反复发作且病因不明的溃疡性结肠炎和克隆病二者。这两种疾病在肠道均有多发性炎症和溃疡,以腹泻、便血及腹痛为主要症状,有时发生肠穿孔及大量肠出血等严重并发症。由于治疗困难,症状迁延不愈,因而影响患者的日常生活。这两种疾病虽然有以上共同之处,但是其病理改变却完全不同。首先,溃疡性结肠炎的病变部位局限在结肠粘膜,并且为连续性。由于认为可能是病因的细菌和病毒无法鉴定,且往往合并自身免疫性疾病常见的关节痛、皮疹等,因而人们开始注意免疫异常与本病病因病理的关系,结果发现本病患者血清中有抗结肠抗体 Inflammatory bowel disease generally refers to diseases that are predominantly intestinal inflammation, particularly both chronic recurrent and unexplained ulcerative colitis and Crohn’s disease. Both diseases have multiple inflammatory and ulceration in the intestine, diarrhea, blood in the stool and abdominal pain as the main symptoms, intestinal perforation and sometimes a large number of intestinal bleeding and other serious complications. Due to the difficulty of treatment, the symptoms of delayed healing, thus affecting the patient’s daily life. Although these two diseases have the above common features, their pathological changes are completely different. First of all, ulcerative colitis lesions confined to the colonic mucosa, and for the continuity. As the bacteria and viruses that may be the cause of the disease can not be identified, and often combined with autoimmune diseases common joint pain, rash, etc., and thus people began to pay attention to the relationship between the immune abnormalities and the etiology and pathology, found that patients with serum anti- Colon antibody