侵袭性真菌感染是一种严重危及生命的真菌病,死亡率较高。艾沙康唑是一种广谱的用于治疗成人侵袭性曲霉菌病和毛霉菌病引起的严重感染的抗真菌药物,于2015年3月6日被美国FDA批准上市。本文综述艾沙康唑的作用机制、药动学、药效学、临床试验、不良反应及药物相互作用。 Invasive fungal infection is a serious life-threatening fungal disease with a high mortality rate. Isaconazole is a broad-spectrum antifungal drug for the treatment of severe infections caused by invasive aspergillosis and mucormycosis in adults and was approved by the FDA for marketing on March 6, This article reviews the mechanism of action of isaconconazole, pharmacokinetics, pharmacodynamics, clinical trials, adverse reactions and drug interactions.