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目的:探讨羟甲唑啉(商品名:达芬霖)在小儿鼻内镜手术中的应用价值。方法:观察鼻内镜手术中应用羟甲唑啉对患儿的脉搏、血压的影响,出现反跳的时间及术中出血量的多少。结果:在羟甲唑啉应用前后,72例患者的脉搏及血压变化差异均无统计学意义(均P>0.05),降低鼻血流量约50%,作用持续时间长达6h。结论:羟甲唑啉作为鼻黏膜血管减充剂和麻醉辅助药可常规用于小儿鼻内镜手术,且安全、有效。
Objective: To investigate the value of oxymetazoline (brand name: Da Fenlin) in pediatric endoscopic sinus surgery. Methods: To observe the effect of oxymetazoline on the pulse and blood pressure in nasal endoscopic surgery, the time of rebound and the amount of intraoperative blood loss. Results: Before and after oxymetazoline treatment, there was no significant difference in pulse and blood pressure among 72 patients (all P> 0.05). The decrease of the blood flow was about 50% and the duration of action was up to 6 hours. CONCLUSION: Oxymetazoline can be routinely used in pediatric endoscopic sinus surgery as a nasal mucosal vasodilator and anesthetic adjuvant and is safe and effective.