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目的:为在高原地区建立无痛分娩检测体系，推广无痛分娩理念，降低剖宫产率，进行西藏地区无痛分娩的临床研究。方法:通过前瞻性研究，收集2018年1月至2019年6月拉萨市人民医院150例初产妇，符合无痛分娩适应证且无禁忌证，随机数字表法分为舒芬太尼复合罗哌卡因组(A组，n n＝50)、芬太尼复合罗哌卡因组(B组，n n＝50)及未采取镇痛的对照组(C组，n n＝50)；收集产妇分娩前后一般情况，采用视觉模拟量表(VAS)评分，观察记录分娩进程及结果，进行新生儿Apgar评分并取脐动脉血进行血气分析。n 结果:A组和B组第一产程和第二产程均较C组时间短(n P0.05)。A组和B组VAS评分均低于C组(n P0.05)。三组脐动脉血pH值比较差异无统计学意义(n P>0.05)。A组与B组产妇POn 2均高于C组(n P0.05)。A组与B组脐动脉血PCOn 2均低于C组(n P0.05)。C组产妇剖宫产率高于A组和B组(n P0.05)，但三组产妇新生儿总体不良情况发生率差异有统计学意义(n P0.05). The umbilical artery blood POn 2 of group A and group B was higher than those of group C (n P0.05). The umbilical artery blood PCOn 2 of group A and group B was lower than that of group C(n P0.05). The cesarean section rate in group C was higher than that in groups A and B (n P0.05). There was significant difference in the overall incidence of adverse conditions in the three groups (n P<0.05). The Apgar scores of the newborns in groups A and B were higher than those in the C group at 1 min postpartum (n P0.05).n Conclusions:Painless delivery in plateau area can reduce the pain of delivery and the rate of cesarean section, and has high safety and reduce the adverse effects on mothers and infants, which is worthy of clinical promotion.