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目的通过对绒毛和羊水的检测弄清弓形虫宫内感染情况以降低先天畸形儿的出生。方法用ＥＬＩＳＡ法和小白鼠腹腔培养法，对１０４份绒毛和４９４份羊水进行了检测。结果证实弓形虫宫内感染绒毛组为１８．１９％；羊水组为４．５６％。经抗弓形虫治疗后，羊水ＩｇＭ和ＣＡｇ阳性率为３．８６％（未治组为１１．８５％），异常产为２．５６％（未治组为１８．２９％）。结论对血清免疫学阳性的孕妇应避免宫内感染。用羊水监测可以诊断和控制弓形虫病母子垂直传播，但早期防治比羊水监测效果更好。
Objective To understand the intrauterine infection of toxoplasma by detecting villus and amniotic fluid to reduce the birth of congenital malformation. Methods Using ELISA and celiac culture, 104 villus and 494 amniotic fluid were tested. The results confirmed that Toxoplasma gondii infection in villus group was 18.19%; amniotic fluid group was 4.56%. After anti-toxoplasma treatment, the positive rates of IgM and CAg in amniotic fluid were 3.86% (11.85% in the untreated group) and 2.56% in the untreated group (18.29% in the untreated group). Conclusion Pregnant women with positive serum immunology should avoid intrauterine infection. With amniotic fluid monitoring can diagnose and control toxoplasmosis mother and child vertical transmission, but the early prevention and treatment better than amniotic fluid monitoring.