论文部分内容阅读
目的：探讨新生儿缺氧缺血性脑病（HIE）的预后情况。材料与方法：选择围产期有窒息史，MRI及临床诊断为不同程度HIE的新生儿30例，分别于3个月、6个月、1岁、2岁、3岁以前进行MRI和临床复查，6例行MRI复查2～3次。结果：全部病例显示HIE所致脑水肿消失，6例轻度和3例中度HIE患者在1岁内复查示外部性脑积水，其中6例在1岁后再次复查见外部性脑积水消失，15例中度和6例重度HIE示髓鞘发育延迟，局部脑软化，脑室周围白质软化，脑萎缩。结论：HIE的预后与MRI分度密切相关，轻度者预后良好，中、重度预后差。
Objective: To investigate the prognosis of neonatal hypoxic-ischemic encephalopathy (HIE). MATERIALS AND METHODS: Thirty newborns with perinatal asphyxia, MRI and clinically diagnosed HIE were enrolled in this study. MRI and clinical review were performed at 3 months, 6 months, 1 year, 2 years and 3 years of age respectively , 6 cases of MRI review 2 to 3 times. Results: All the cases showed that cerebral edema caused by HIE disappeared. Six mild and three moderate HIE patients were examined with external hydrocephalus within 1 year of age. Of the 6 cases, external hydrocephalus Disappeared, 15 cases of moderate and 6 cases of severe HIE showed delayed myelin development, local brain softening, periventricular white matter softening, brain atrophy. Conclusion: The prognosis of HIE is closely related to the MRI classification. The mild prognosis is good, and the moderate and severe prognosis is poor.