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本文对一组25~35岁健康志愿者分别使用0.1~0.8毫克阿托品,评价它对窦房结和房室结的药理作用,其结果如下表: 阿托品为迷走神经拮抗剂,在静注后25秒钟即起作用,高峰时间为2~3分钟。已证实副交感神经兴奋可使窦房率减少,房室传导时间延长。副交感神经被药物阻滞则引起窦房率增加和房室传导时间缩短。
In this paper, a group of 25-35 healthy volunteers were used 0.1 ~ 0.8 mg atropine, evaluation of its pharmacological effects on the sinus node and atrioventricular node, the results are as follows: Atropine vagus nerve antagonist, 25 seconds after intravenous injection Clock is working, the peak time is 2 to 3 minutes. Parasympathetic nerve stimulation has been confirmed that can reduce the rate of sinoatrial, atrioventricular conduction time. Parasympathetic nerve blockage caused by the drug is increased sinoatrial room and atrioventricular conduction time is shortened.