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报道５例无功能性胰岛细胞瘤，结合国内７１例的文献资料作一综合分析。男性２３例，女性５３例。年龄最小者１１岁，最大者６０岁，大多在２０～４５岁之间。肿瘤部位有明确记录６５例，分布在头部３６例，体部１６例，尾部１２例，全胰腺１例。良性５６例（７３．７％）；恶性２０例（２６．３％），其中３例发生转移，１７例主要是局部浸涧至邻近脏器和血管。肿瘤直径大多＞６ｃｍ，最大者为２５ｃｍ。囊性变３３／７６例（４３．４％）。肿瘤大多有完整包膜，向胰外突出生长，基底部大多不很宽。鉴于本病即使是良性，局部生长也不能被控制的生物学行为。我们认为应将瘤细胞异形性、核分裂相和瘤细胞侵犯被膜或血管作为诊断恶性的标准。本病术前确诊困难，尤其是发生较大囊性变时，Ｂ超、ＣＴ和血管造形等均难以与胰腺囊腺瘤和／或囊腺癌作出鉴别。本病如为良性，手术方式决定于肿瘤部位及其与胰管的关系，完整摘除肿瘤或连同肿瘤在内的胰腺部分切除；如为恶性，则手术适应证和手术方式的选择同胰腺癌。
Five cases of non-functioning islet cell tumors were reported, and a comprehensive analysis was made based on the literature data of 71 cases in China. There were 23 males and 53 females. The youngest are 11 years old and the oldest are 60 years old, most of whom are between 20 and 45 years old. The tumor site was clearly recorded in 65 cases, distributed in the head 36 cases, body 16 cases, tail 12 cases, 1 case of pancreas. 56 cases were benign (73.7%); 20 cases were malignant (26.3%), of which 3 cases had metastasis, and 17 cases were mainly localized to adjacent organs and blood vessels. Most of the tumors were >6cm in diameter, and the largest was 25cm. Cystic changes 33/76 cases (43.4%). Most of the tumors have a complete capsule, which protrudes out of the pancreas and most of the base is not very wide. In view of the benign nature of the disease, local growth cannot be controlled biological behavior. We believe that the abnormality of tumor cells, mitotic facies, and invasion of tumor cells or blood vessels should be the criteria for the diagnosis of malignancy. The preoperative diagnosis of the disease is difficult, especially when a large cystic change occurs, B-ultrasonography, CT and vascular shape and other difficult to distinguish with pancreatic cystadenoma and / or cystadenocarcinoma. If the disease is benign, the surgical method is determined by the location of the tumor and its relationship with the pancreatic duct, complete removal of the tumor or partial removal of the pancreas together with the tumor; if malignant, the indication for surgery and the choice of surgical approach are the same as pancreatic cancer.