糖尿病视网膜病变是糖尿病致盲的重要并发症,是以血管改变为核心的。血管内皮功能障碍是糖尿病血管并发症的始发因素。内皮祖细胞(endothelial progenitor cells,EPCs),它能进一步分化为内皮细胞而参与受损血管内皮的修复与血管新生。EPCs移植治疗DR一个新的途径,相关研究取得了很大的进展。文中就DR的核心发病机理、EPCs与DR血管损伤修复的关系、EPCs移植治疗DR的现状以及展望进行综述。 Diabetic retinopathy is an important complication of blindness caused by diabetes and is based on the changes of blood vessels. Vascular endothelial dysfunction is a contributing factor to vascular complications of diabetes. Endothelial progenitor cells (EPCs), which can further differentiate into endothelial cells, are involved in the repair of damaged vascular endothelium and angiogenesis. EPCs transplantation for the treatment of DR a new way, the relevant research has made great progress. In this paper, the core pathogenesis of DR, the relationship between EPCs and DR vascular repair, the current situation and prospects of EPCs transplantation for treatment of DR were reviewed.