目前临床使用的三磷酸腺甙注射液(简称ATP针),不论是冰冻干燥品或水针剂,经肌注后,病人普遍反映注射局部疼痛,特别是加有缓冲剂的制剂,疼痛尤甚。为了减轻患者因注射ATP针而引起疼痛,经多次实验,找出了一个注后既无痛,而制剂又较稳定,于100℃加热120分钟,ATP仅分解8％左右的配方,供具一般设备条件的单位生产ATP针作参考。 Clinical application of adenosine triphosphate injection (ATP needle for short), whether it is freeze-dried or water injection, the intramuscular injection, the patient generally reflects the injection of local pain, especially with a buffer formulation, especially pain. In order to reduce the pain caused by injection of ATP needle in patients, after several experiments, we found out that there is no pain after injection, while the preparation is more stable, heated at 100 ℃ for 120 minutes, ATP only decomposed about 8% General equipment conditions of the unit to produce ATP needle for reference.