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自1963年由Abelev首次报告甲胎蛋白(AFP)以来,AFP在诊断原发性肝癌(PHC)方面一直起着重要的作用,但它还存在着30％左右的假阴性和低浓度问题,并且对继发性肝癌(MHC)不易测出,这给临床正确诊断带来了一定困难。目前临床上尚未普及利用的通过定性方法测定耐温达61±0.1℃的特异性γ——谷氨酰转移酶完全可以弥补AFP的不足,它对PHC和MHC诊断结果都较满意。1 材料和方法1.1 检测对象:59例肝癌患者均为市内几家医院的住院患者,其中诊断为PHC38例,MHC21例,均经临床综合检查或病理检查证实诊断。所有
Since Abelev first reported alpha-fetoprotein (AFP) in 1963, AFP has been playing an important role in the diagnosis of primary liver cancer (PHC), but it still has about 30% false negative and low concentrations, and It is not easy to detect secondary liver cancer (MHC), which brings certain difficulties to clinical diagnosis. At present, the specific gamma-glutamyltransferase, which has not been universally used in clinical practice, measures temperature resistance at 61±0.1°C and can completely compensate for the deficiency of AFP. It is satisfactory for both PHC and MHC diagnostic results. 1 Materials and methods 1.1 Detection objects: 59 cases of liver cancer patients were hospitalized in several hospitals in the city, of which 38 cases were diagnosed as PHC and 21 cases were MHC. All were diagnosed by clinical comprehensive examination or pathological examination. all