宫颈上皮内瘤变的发病率在育龄期女性中有逐渐上升的趋势,对女性的身体健康及生活质量有着较大的影响,尤其是高级别上皮内瘤变,即CINⅡ及Ⅲ,被认为是宫颈癌的癌前病变。宫颈内上皮内瘤变的正确诊断和合理治疗日渐受到人们的关注。就宫颈上皮内瘤变的病因、部分相关蛋白、诊断、治疗及随访等方面的内容进行了简单的总结。 The incidence of cervical intraepithelial neoplasia in women of childbearing age have a rising trend, the health and quality of life of women have a greater impact, especially high-grade intraepithelial neoplasia, CIN Ⅱ and Ⅲ, is considered to be Cervical precancerous lesions. The correct diagnosis and reasonable treatment of cervical intraepithelial neoplasia have drawn more and more attention. The etiology of cervical intraepithelial neoplasia, some related proteins, diagnosis, treatment and follow-up were briefly summarized.