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本研究旨在评估正常人胃十二指肠粘膜中转化生长因子-α(TGF-α)和表皮生长因子(EGF)的浓度和区域性分布,并研究了伴或不伴有充血性胃病的慢性肝病患者中TGF-α和EGF的浓度。 材料和方法:31例受试者,经肝脏活检确诊,其中分为三组:组1.12例慢性肝炎(男性9例,女性3例,21～73岁);组2.8例肝硬化(男性3例,女性5例,46～79岁),无胃镜下充血性胃病、食管静脉曲张及B超下也未见门脉高压征象;组3.11例肝硬化患者(男性8名,女性3名,39～73岁),伴有充血性胃病、食管静脉曲张及
The aim of this study was to evaluate the concentration and regional distribution of TGF-α and EGF in normal human gastroduodenal mucosa and to investigate the relationship between the concentration and regional distribution of transforming growth factor-α (TGF-α) and epidermal growth factor (EGF) Concentrations of TGF-α and EGF in patients with chronic liver disease. Materials and Methods: Twenty-one subjects were diagnosed by liver biopsy and divided into three groups: group 1.12 cases of chronic hepatitis (9 males and 3 females, 21-73 years old); group 2, cirrhosis (3 males , 5 female, 46-79 years old). No gastroduodenal congestive gastropathy, esophageal varices and B-ultrasonography showed no signs of portal hypertension. Group 3.11 patients with cirrhosis (8 males, 3 females, 73 years old), with congestive stomach, esophageal varices and